ω-Transaminase from Ochrobactrum anthropi Is Devoid of Substrate and Product Inhibitions
نویسندگان
چکیده
منابع مشابه
ω-Transaminase from Ochrobactrum anthropi is devoid of substrate and product inhibitions.
ω-Transaminases display complicated inhibitions by ketone products and both enantiomers of amine substrates. Here, we report the first example of ω-transaminase devoid of such inhibitions. Owing to the lack of enzyme inhibitions, the ω-transaminase from Ochrobactrum anthropi enabled efficient kinetic resolution of α-methylbenzylamine (500 mM) even without product removal.
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2013
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.03811-12